Tramadol: Reliable Synthetic Analgesic for Research Applications

At GlobalChemSolutions.com, we provide high-quality research chemicals to labs and scientific institutions around the world. One of our featured compounds is Tramadol, a synthetic analgesic widely used in pain pathway research, opioid receptor studies, and pharmacokinetic modeling.

Known for its dual mechanism of action, Tramadol interacts with both opioid and monoamine systems, making it a powerful subject for researchers focused on pain modulation, serotonin-norepinephrine interaction, and synthetic opioid design.

⚠️ Note: Tramadol sold by GlobalChemSolutions is intended strictly for laboratory use only. It is not for human or animal use under any circumstances.

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What is Tramadol?

Tramadol is a centrally acting synthetic analgesic with opioid and non-opioid properties. Structurally related to codeine, it has been used in clinical contexts to treat moderate to severe pain but also presents significant scientific value in receptor binding studies and analytical toxicology.

• IUPAC Name: (±)-cis-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol

• CAS Number: 27203-92-5

• Molecular Formula: C16H25NO2

• Molar Mass: 263.38 g/mol

• Form: White crystalline powder

• Purity: ≥98% (HPLC/GC Verified)

• Storage: Cool, dry environment away from direct light

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Key Characteristics of Tramadol

• ✅ Synthetic analgesic with dual action

• ✅ μ-opioid receptor agonist

• ✅ Inhibits serotonin and norepinephrine reuptake

• ✅ Ideal for pain mechanism and CNS research

• ✅ Useful in metabolism and toxicokinetics studies

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Scientific Applications of Tramadol

1. Pain Pathway and Analgesia Research

Tramadol is commonly used in laboratory settings to study pain modulation pathways through both opioid receptor interaction and monoamine modulation. It helps researchers model neuropathic and chronic pain conditions.

2. Opioid Receptor Binding Studies

Tramadol binds to the μ-opioid receptor, although with lower affinity than morphine or oxycodone. This makes it ideal for comparative receptor profiling and assessing the role of partial agonism in pain relief.

3. Monoamine Transporter Analysis

Tramadol inhibits serotonin and norepinephrine reuptake, contributing to its analgesic effects. Researchers can use it to study serotonergic and adrenergic systems, especially in CNS disorders and antidepressant models.

4. Pharmacokinetics and Metabolism

With active metabolites like O-desmethyltramadol (M1), Tramadol offers insight into CYP2D6 enzyme pathways, drug metabolism, and individual variability in drug response.

5. Toxicology and Forensic Applications

Tramadol is included in postmortem toxicology panels, drug screening methods, and substance abuse studies. Researchers use it to create and validate quantitative detection methods using HPLC, LC-MS/MS, and GC-MS.

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Why Order Tramadol from GlobalChemSolutions?

GlobalChemSolutions ensures every compound meets rigorous quality and safety standards. Our Tramadol is manufactured under controlled conditions and tested to ensure purity, consistency, and documentation support.

When you choose us, you get:

• Lab-Tested ≥98% Purity

• Certificate of Analysis (COA) Included

• Secure, Encrypted Checkout

• Fast and Discreet International Shipping

• Dedicated Support for Scientific Queries

We package all chemicals in tamper-proof, moisture-resistant containers for safe storage and delivery.

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Storage & Handling Guidelines

• Store Tramadol in a sealed container in a cool, dry location, protected from heat and light.

• Always wear gloves, goggles, and protective clothing when handling.

• Follow all relevant lab safety protocols for synthetic opioids.

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Legal Considerations

Tramadol is a controlled substance in many countries due to its opioid-like effects. While we only sell Tramadol to licensed institutions and verified researchers, it is the buyer’s responsibility to ensure they are complying with local laws and regulations regarding possession and importation.

GlobalChemSolutions does not ship to jurisdictions where Tramadol is restricted or banned.

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Final Thoughts

Tramadol is a valuable tool in neuroscience, pharmacology, and toxicology research. Its unique action on both opioid receptors and monoamine systems offers broad applications in modern pain science and drug development.

At GlobalChemSolutions.com, we are committed to delivering high-purity Tramadol to support your critical research. With fast shipping, reliable documentation, and responsive service, we help professionals like you make meaningful scientific progress.