AMT (Alpha-Methyltryptamine): A Potent Tryptamine for Advanced Research

At GlobalChemSolutions.com, we supply professional researchers with reliable, lab-tested chemicals to support cutting-edge science. One of our most requested compounds in the tryptamine family is AMT (Alpha-Methyltryptamine)—a synthetic molecule known for its unique activity within serotonergic and dopaminergic systems.

AMT holds strong value in the study of psychoactive compounds, neurotransmitter interaction, and central nervous system (CNS) function. Originally developed in the mid-20th century, it has resurfaced in modern laboratories for its structural similarity to serotonin and its interesting pharmacological behavior.

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What is AMT?

AMT is a synthetic, alpha-substituted tryptamine, classified under the indoleamine class of psychoactive research compounds. It shares structural features with naturally occurring neurotransmitters and acts as a monoamine releasing agent (MRA) and reuptake inhibitor.

• Full Name: Alpha-Methyltryptamine

• Molecular Formula: C11H14N2

• Molar Mass: 174.24 g/mol

• CAS Number: 61-50-7

• Appearance: Off-white crystalline powder

• Purity: ≥98% (HPLC Verified)

• Use: For scientific research only

The addition of the alpha-methyl group increases AMT’s oral bioavailability and duration, making it an ideal compound for studying long-acting serotonergic agents.

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Why Researchers Use AMT

• ✅ Long-lasting activity for extended observation

• ✅ Releases serotonin, dopamine, and norepinephrine

• ✅ Non-selective monoamine releasing agent (SNDRA)

• ✅ Tryptamine backbone similar to endogenous compounds

• ✅ Useful for receptor profiling and neurochemical mapping

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Applications in Scientific Research

⚠️ For research use only. Not for human or veterinary use.

1. Receptor Binding Studies

AMT is commonly used to study the 5-HT2A receptor, as well as dopaminergic and adrenergic systems. It provides insight into how non-selective monoamine releasers affect the brain.

2. Pharmacokinetics & Metabolism Research

Due to its unique structure and long half-life, AMT is ideal for exploring metabolic pathways, absorption models, and central nervous system penetration.

3. Structure-Activity Relationship (SAR)

AMT serves as a reference point in SAR studies focused on tryptamine derivatives. Researchers compare its effects to other compounds like DMT, 5-MeO-DMT, and alpha-ethyltryptamine (AET).

4. Forensic Toxicology & Drug Identification

AMT has appeared in forensic cases involving novel psychoactive substances (NPS). Labs use it to develop analytical detection methods using GC-MS, HPLC, and FTIR.

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Why Buy AMT from GlobalChemSolutions?

At GlobalChemSolutions, we provide high-purity AMT to qualified researchers across the globe. We ensure each batch meets the highest standards of chemical accuracy and consistency.

Here’s why scientists trust us:

• ≥98% Lab-Tested Purity

• Certificate of Analysis (COA) Included

• Rapid, Discreet Global Shipping

• Secure Payment Processing

• Dedicated Research Support Team

Every order is handled with care, packaged securely, and accompanied by documentation to support your lab’s compliance and workflow.

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Handling & Storage Recommendations

To preserve stability, store AMT in a cool, dry environment, away from sunlight and moisture. Use protective gloves, eyewear, and a lab coat when handling. Always follow your institution’s safety protocols for synthetic tryptamines.

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Legal Information

AMT is unscheduled in several countries, but local laws vary. In some jurisdictions, it may be controlled under analog acts or psychoactive substance regulations. It is your responsibility to ensure that AMT is legal to possess and import in your area.

GlobalChemSolutions will not ship AMT to regions where it is restricted.

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Final Thoughts

Alpha-Methyltryptamine (AMT) is a highly valuable compound in psychedelic and neurochemical research. Its ability to influence multiple neurotransmitter systems makes it a powerful tool in understanding how the brain responds to monoamine modulation.

At GlobalChemSolutions.com, we’re proud to offer AMT of the highest quality, delivered fast and backed by professional documentation. Explore new frontiers in serotonergic research, pharmacology, and analytical science—with AMT from a supplier you can trust.